ABSTRACT
A retrospective evaluation (1999 to 2004) of all 1,875 necropsies was performed at one Veterinory Pathology Service in Brazil with the aim of characterizing the cases of fatal poisonings in dogs and cats. During this period, 261 (13.9%) cases of dog or cat poisoning were identified. For all animals the exposures were of acute nature, caused by a single substance, occurred by ingestion and the most them were of intentional nature. The main agent was aldicorb responsible for 88.6% of the intoxications in dogs and 95.0% in cats. Other agents were anticoagulants (10.0% in dogs and 0.8% in cats), sodium monofluoracetate (1.4% in dogs) and no specified organic solvent (4.2% in cats).
Um levantamento retrospectivo (1999-2004) de 1.875 necropsias foi realizado em um Serviço de Patologia Veterinária brasileiro com o objetivo de caracterizar os casos de intoxicação fatal em cães e gatos. Durante este período, 261 (13,9%) cães e gatos tiveram como causa mortis a intoxicação exógena. Em todos os casos, a intoxicação foi de caráter agudo, causada por um único agente tóxico e, na maioria das vezes, de natureza intencional. O carbamato aldicarb foi o agente tóxico mais comum em ambas espécies, sendo responsável por 88,6% dos casos de intoxicação em cães e 95.0% dos casos em gatos. Outros agentes tóxicos encontrados foram o fluoroacetato de sódio (1,4% - em cães) e um solvente orgânico não especificado (4,7% - em gatos).
Subject(s)
Animals , Aldicarb/toxicity , Cats , Dogs , Pathology, Veterinary , Pesticides/toxicityABSTRACT
Individual and combined toxicity of three pesticides, endosulfan, phosphamidon, and aldicarb was evaluated in P. conchonius. The 48 hr LC50 was 21.36 and 446.5 ppm respectively for endosulfan and phosphamidon. When tested jointly, 48 hr LC50 for different ratios of these pesticides were 0.332 (IE:3P), 0.224 (IE:1P), and 0.178 ppm (3E:1P). The cotoxicity coefficients for these combinations were 1793, 3986, and 10009, respectively. An equitoxic mixture of endosulfan, phosphamidon, and aldicarb yielded a 48 hr LC50 of 130.5 ppm. An enhanced toxic impact is indicated when the pesticides are present together rather than as individual compounds.